ID   HNPSV-1
AC   CVCL_B0BI
SY   Human Nucleus Pulposus SV40-transformed-1
DR   Wikidata; Q108820490
RX   PubMed=15247572;
RX   PubMed=16102816;
RX   PubMed=19598131;
CC   Population: Japanese.
CC   Senescence: Transformed but with a finite life span. Senesces at 60-100 PDL (PubMed=15247572).
CC   Transformant: Ad12-SV40 hybrid virus.
CC   Derived from site: In situ; Intervertebral disc, nucleus pulposus; UBERON=UBERON_0002242.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   19Y
CA   Transformed cell line
DT   Created: 23-09-21; Last updated: 29-06-23; Version: 5
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RX   PubMed=15247572; DOI=10.1097/01.brs.0000131419.25265.23;
RA   Sakai D., Mochida J., Yamamoto Y., Toh E., Iwashina T., Miyazaki T.,
RA   Inokuchi S., Ando K., Hotta T.;
RT   "Immortalization of human nucleus pulposus cells by a recombinant SV40
RT   adenovirus vector: establishment of a novel cell line for the study
RT   of human nucleus pulposus cells.";
RL   Spine 29:1515-1523(2004).
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RX   PubMed=16102816; DOI=10.1016/j.biomaterials.2005.06.040;
RA   Sakai D., Mochida J., Iwashina T., Watanabe T., Suyama K., Ando K.,
RA   Hotta T.;
RT   "Atelocollagen for culture of human nucleus pulposus cells forming
RT   nucleus pulposus-like tissue in vitro: influence on the proliferation
RT   and proteoglycan production of HNPSV-1 cells.";
RL   Biomaterials 27:346-353(2006).
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RX   PubMed=19598131; DOI=10.22203/ecm.v017a02;
RA   Kobayashi Y., Sakai D., Iwashina T., Iwabuchi S., Mochida J.;
RT   "Low-intensity pulsed ultrasound stimulates cell proliferation,
RT   proteoglycan synthesis and expression of growth factor-related genes
RT   in human nucleus pulposus cell line.";
RL   Eur. Cell. Mater. 17:15-22(2009).
//