ID   HNPSV-1
AC   CVCL_B0BI
SY   Human Nucleus Pulposus SV40-transformed-1
DR   Wikidata; Q108820490
RX   PubMed=15247572;
RX   PubMed=16102816;
RX   PubMed=19598131;
CC   Population: Japanese.
CC   Senescence: Transformed but with a finite life span. Senesces at 60-100 PDL (PubMed=15247572).
CC   Transformant: Ad12-SV40 hybrid virus.
CC   Derived from site: In situ; Intervertebral disc, nucleus pulposus; UBERON=UBERON_0002242.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   19Y
CA   Transformed cell line
DT   Created: 23-09-21; Last updated: 29-06-23; Version: 5
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RX   PubMed=16102816; DOI=10.1016/j.biomaterials.2005.06.040;
RA   Sakai, Daisuke
RA   Mochida, Joji
RA   Iwashina, Toru
RA   Watanabe, Takuya
RA   Suyama, Kaori
RA   Ando, Kiyoshi
RA   Hotta, Tomomitsu
RT   "Atelocollagen for culture of human nucleus pulposus cells forming
RT   nucleus pulposus-like tissue in vitro: influence on the proliferation
RT   and proteoglycan production of HNPSV-1 cells.";
RL   Biomaterials 27:346-353(2006).
//
RX   PubMed=15247572; DOI=10.1097/01.brs.0000131419.25265.23;
RA   Sakai, Daisuke
RA   Mochida, Joji
RA   Yamamoto, Yukihiro
RA   Toh, Eiren
RA   Iwashina, Toru
RA   Miyazaki, Takeshi
RA   Inokuchi, Sadaki
RA   Ando, Kiyoshi
RA   Hotta, Tomomitsu
RT   "Immortalization of human nucleus pulposus cells by a recombinant SV40
RT   adenovirus vector: establishment of a novel cell line for the study
RT   of human nucleus pulposus cells.";
RL   Spine 29:1515-1523(2004).
//
RX   PubMed=19598131; DOI=10.22203/ecm.v017a02;
RA   Kobayashi, Yuka
RA   Sakai, Daisuke
RA   Iwashina, Toru
RA   Iwabuchi, Sadahiro
RA   Mochida, Joji
RT   "Low-intensity pulsed ultrasound stimulates cell proliferation,
RT   proteoglycan synthesis and expression of growth factor-related genes
RT   in human nucleus pulposus cell line.";
RL   Eur. Cell. Mater. 17:15-22(2009).
//