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Cellosaurus CX16-8 TZ (CVCL_B0AT)

[Text version]
Cell line name CX16-8 TZ
Synonyms 16-8 TZ
Accession CVCL_B0AT
Resource Identification Initiative To cite this cell line use: CX16-8 TZ (RRID:CVCL_B0AT)
Comments Characteristics: Transfected with the plasmid pMHPV16d, which contains two copies of the complete HPV16 genome in a head-to-tail configuration (PubMed=29944714).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Uterus, cervix, cervical transformation zone epithelium; UBERON=UBERON_8480035.
Cell type: Epithelial cell; CL=CL_0000066.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_B0AR ! CX16-8 Ecto
CVCL_B0AS ! CX16-8 Endo
Sex of cell Female
Age at sampling Age unspecified
Category Transformed cell line
STR profile Source(s): PubMed=29944714

Markers:
AmelogeninX
CSF1PO8,10
D5S81811,12
D7S82010,12
D13S31711,12
D16S53910
TH017,8
TPOX8,11
vWA15,16

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Publications

PubMed=29944714; DOI=10.1371/journal.pone.0199761; PMCID=PMC6019754
Deng H., Hillpot E., Yeboah P., Mondal S., Woodworth C.D.
Susceptibility of epithelial cells cultured from different regions of human cervix to HPV16-induced immortalization.
PLoS ONE 13:e0199761.1-e0199761.16(2018)

PubMed=30337615; DOI=10.1038/s41598-018-33865-2; PMCID=PMC6194146
Deng H., Hillpot E., Mondal S., Khurana K.K., Woodworth C.D.
HPV16-immortalized cells from human transformation zone and endocervix are more dysplastic than ectocervical cells in organotypic culture.
Sci. Rep. 8:15402-15402(2018)

Cross-references
Encyclopedic resources Wikidata; Q108820104
Entry history
Entry creation23-Sep-2021
Last entry update10-Sep-2024
Version number6