ID   CX16-RV2 TZ
AC   CVCL_B0AA
DR   ATCC; CRL-3460
DR   Wikidata; Q108820111
RX   PubMed=29944714;
RX   PubMed=30337615;
CC   Doubling time: ~30-40 hours (ATCC=CRL-3460).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
CC   Derived from site: In situ; Uterus, cervix, cervical transformation zone epithelium; UBERON=UBERON_8480035.
CC   Cell type: Epithelial cell; CL=CL_0000066.
ST   Source(s): PubMed=29944714
ST   Amelogenin: X
ST   CSF1PO: 11
ST   D13S317: 12
ST   D16S539: 9,11
ST   D5S818: 11,13
ST   D7S820: 9,10
ST   TH01: 7
ST   TPOX: 9,11
ST   vWA: 15
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_B0A8 ! CX16-RV2 Ecto
OI   CVCL_B0A9 ! CX16-RV2 Endo
SX   Female
AG   Age unspecified
CA   Transformed cell line
DT   Created: 23-09-21; Last updated: 14-08-25; Version: 8
//
RX   PubMed=30337615; DOI=10.1038/s41598-018-33865-2; PMCID=PMC6194146;
RA   Deng, Han
RA   Hillpot, Eric
RA   Mondal, Sumona
RA   Khurana, Kamal K.
RA   Woodworth, Craig D.
RT   "HPV16-immortalized cells from human transformation zone and
RT   endocervix are more dysplastic than ectocervical cells in organotypic
RT   culture.";
RL   Sci. Rep. 8:15402.1-15402.13(2018).
//
RX   PubMed=29944714; DOI=10.1371/journal.pone.0199761; PMCID=PMC6019754;
RA   Deng, Han
RA   Hillpot, Eric
RA   Yeboah, Philomina
RA   Mondal, Sumona
RA   Woodworth, Craig D.
RT   "Susceptibility of epithelial cells cultured from different regions of
RT   human cervix to HPV16-induced immortalization.";
RL   PLoS ONE 13:e0199761.1-e0199761.16(2018).
//