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Cellosaurus HeLa IFITM2/3-KO (CVCL_B0A5)

[Text version]
Cell line name HeLa IFITM2/3-KO
Synonyms IFITM2/3 Knockout; C5-2
Accession CVCL_B0A5
Resource Identification Initiative To cite this cell line use: HeLa IFITM2/3-KO (RRID:CVCL_B0A5)
Comments Population: African American.
Knockout cell: Method=CRISPR/Cas9; HGNC; 5413; IFITM2.
Knockout cell: Method=CRISPR/Cas9; HGNC; 5414; IFITM3.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Publications

PubMed=30643282; DOI=10.1038/s41589-018-0213-2
Spence J.S., He R.-N., Hoffmann H.-H., Das T., Thinon E., Rice C.M., Peng T., Chandran K., Hang H.C.
IFITM3 directly engages and shuttles incoming virus particles to lysosomes.
Nat. Chem. Biol. 15:259-268(2019)

Cross-references
Encyclopedic resources Wikidata; Q108820453
Entry history
Entry creation23-Sep-2021
Last entry update05-Oct-2023
Version number5