Cellosaurus HeLa IFITM1/2/3-KO (CVCL_B0A4)
| Cell line name | HeLa IFITM1/2/3-KO | ||||||||||||||||||
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| Synonyms | IFITM1/2/3 Knockout; C5-9 | ||||||||||||||||||
| Accession | CVCL_B0A4 | ||||||||||||||||||
| Resource Identification Initiative | To cite this cell line use: HeLa IFITM1/2/3-KO (RRID:CVCL_B0A4) | ||||||||||||||||||
| Comments | Population: African American. Characteristics: Facilitates the functional analysis of IFITMs and as well as their mechanisms of regulation. Can also be used to identify other innate immunity factors and/or screen for new anti-infective drug candidates (ATCC=CRL-3452). Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:5412; IFITM1. Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:5413; IFITM2. Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:5414; IFITM3. Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18). Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002. | ||||||||||||||||||
| Disease | Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677) | ||||||||||||||||||
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||
| Hierarchy | Parent: CVCL_0030 (HeLa) | ||||||||||||||||||
| Sex of cell | Female | ||||||||||||||||||
| Age at sampling | 30Y6M | ||||||||||||||||||
| Category | Cancer cell line | ||||||||||||||||||
| STR profile | Source(s): ATCC=CRL-3452 Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
| Publications | PubMed=30643282; DOI=10.1038/s41589-018-0213-2; PMCID=PMC6466627 | ||||||||||||||||||
| Cross-references | |||||||||||||||||||
| Cell line collections (Providers) | ATCC; CRL-3452 | ||||||||||||||||||
| Encyclopedic resources | Wikidata; Q108820452 | ||||||||||||||||||
| Entry history | |||||||||||||||||||
| Entry creation | 23-Sep-2021 | ||||||||||||||||||
| Last entry update | 19-Dec-2024 | ||||||||||||||||||
| Version number | 7 | ||||||||||||||||||