ID   CHLA-01-MED
AC   CVCL_B044
DR   ATCC; CRL-3021
DR   BioSample; SAMN03471712
DR   cancercelllines; CVCL_B044
DR   Cosmic; 2772986
DR   Wikidata; Q54812135
RX   PubMed=24300787;
RX   PubMed=25211508;
RX   PubMed=26380221;
RX   PubMed=27498314;
RX   PubMed=27812533;
CC   Sequence variation: Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Ser1982Argfs*22 (c.5946delT) (6174delT); ClinVar=VCV000009325; Zygosity=Heterozygous (PubMed=26380221).
CC   Omics: Array-based CGH.
CC   Omics: CNV analysis.
CC   Derived from site: In situ; Brain, cerebellum; UBERON=UBERON_0002037.
ST   Source(s): ATCC=CRL-3021
ST   Amelogenin: X,Y
ST   CSF1PO: 11
ST   D13S317: 8,14
ST   D16S539: 9,11
ST   D18S51: 13,17
ST   D19S433: 15
ST   D21S11: 27,29
ST   D2S1338: 18,24
ST   D3S1358: 16,17
ST   D5S818: 11,13
ST   D7S820: 10
ST   D8S1179: 13
ST   FGA: 22,25
ST   Penta D: 11,14
ST   Penta E: 14,19,20
ST   TH01: 6,9.3
ST   TPOX: 9,12
ST   vWA: 16,17
DI   NCIt; C129446; Medulloblastoma, non-WNT/non-SHH, group 4
DI   ORDO; Orphanet_616; Medulloblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_N534 ! CHLA-01R-MED
SX   Male
AG   8Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 19-12-24; Version: 19
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RX   PubMed=24300787; DOI=10.1158/1078-0432.CCR-13-2053; PMCID=PMC3962776;
RA   Erdreich-Epstein A., Robison N., Ren X.-H., Zhou H., Xu J.-Y.,
RA   Davidson T.B., Schur M., Gilles F.H., Ji L.-Y., Malvar J.,
RA   Shackleford G.M., Margol A.S., Krieger M.D., Judkins A.R., Jones D.T.W.,
RA   Pfister S.M., Kool M., Sposto R., Asgharzadeh S.;
RT   "PID1 (NYGGF4), a new growth-inhibitory gene in embryonal brain tumors
RT   and gliomas.";
RL   Clin. Cancer Res. 20:827-836(2014).
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RX   PubMed=25211508; DOI=10.1002/jcb.24976; PMCID=PMC10656279;
RA   Xu J., Margol A.S., Asgharzadeh S., Erdreich-Epstein A.;
RT   "Pediatric brain tumor cell lines.";
RL   J. Cell. Biochem. 116:218-224(2015).
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RX   PubMed=26380221; DOI=10.3389/fonc.2015.00191; PMCID=PMC4550790;
RA   Xu J.-Y., Margol A.S., Shukla A., Ren X.-H., Finlay J.L., Krieger M.D.,
RA   Gilles F.H., Couch F.J., Aziz M., Fung E.T., Asgharzadeh S.,
RA   Barrett M.T., Erdreich-Epstein A.;
RT   "Disseminated medulloblastoma in a child with germline BRCA2 6174delT
RT   mutation and without Fanconi anemia.";
RL   Front. Oncol. 5:191.1-191.12(2015).
//
RX   PubMed=27498314; DOI=10.1016/j.jbiotec.2016.07.028;
RA   Ivanov D.P., Coyle B., Walker D.A., Grabowska A.M.;
RT   "In vitro models of medulloblastoma: choosing the right tool for the
RT   job.";
RL   J. Biotechnol. 236:10-25(2016).
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RX   PubMed=27812533; DOI=10.1016/j.dib.2016.10.004; PMCID=PMC5079239;
RA   Ivanov D.P., Walker D.A., Coyle B., Grabowska A.M.;
RT   "Data on the number and frequency of scientific literature citations
RT   for established medulloblastoma cell lines.";
RL   Data Brief 9:696-698(2016).
//