Cellosaurus logo
expasy logo

Cellosaurus A2780/AD10 (CVCL_B037)

[Text version]
Cell line name A2780/AD10
Synonyms A2780-AD10; A2780-AD-10; AD10; AD-10
Accession CVCL_B037
Resource Identification Initiative To cite this cell line use: A2780/AD10 (RRID:CVCL_B037)
Comments Population: African American.
Selected for resistance to: ChEBI; CHEBI:28748; Doxorubicin (Adriablastin; Adriamycin).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Sequence variations
  • Mutation; HGNC; 795; ATM; Simple; p.Pro604Ser (c.1810C>T); ClinVar=VCV000127343; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 9588; PTEN; Simple; p.Lys128_Arg130del (c.383_391del9); Zygosity=Unspecified (from parent cell line).
Disease Ovarian endometrioid adenocarcinoma (NCIt: C7979)
Endometrioid carcinoma of ovary (ORDO: Orphanet_454723)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0134 (A2780)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=8557231; DOI=10.1006/gyno.1996.0014
Skilling J.S., Squatrito R.C., Connor J.P., Niemann T., Buller R.E.
p53 gene mutation analysis and antisense-mediated growth inhibition of human ovarian carcinoma cell lines.
Gynecol. Oncol. 60:72-80(1996)

PubMed=9554442; DOI=10.1093/jnci/90.8.597
Sabichi A.L., Hendricks D.T., Bober M.A., Birrer M.J.
Retinoic acid receptor beta expression and growth inhibition of gynecologic cancer cells by the synthetic retinoid N-(4-hydroxyphenyl) retinamide.
J. Natl. Cancer Inst. 90:597-605(1998)

Cross-references
Cell line databases/resources cancercelllines; CVCL_B037
Anatomy/cell type resources BTO; BTO:0004037
Encyclopedic resources Wikidata; Q54606588
Entry history
Entry creation06-Jun-2012
Last entry update05-Oct-2023
Version number15