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Cellosaurus HSY (CVCL_B032)

[Text version]
Cell line name HSY
Accession CVCL_B032
Resource Identification Initiative To cite this cell line use: HSY (RRID:CVCL_B032)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=20143388; PubMed=29923277). Originally thought to originate from a 51 year old female patient with a parotid gland adenocarcinoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00317.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
STR profile Source(s): JCRB; PubMed=29923277


Run an STR similarity search on this cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx

PubMed=2446043; DOI=10.1093/jnci/79.5.1025
Hayashi Y., Yanagawa T., Yoshida H., Azuma M., Nishida T., Yura Y., Sato M.
Expression of vasoactive intestinal polypeptide and amylase in a human parotid gland adenocarcinoma cell line in culture.
J. Natl. Cancer Inst. 79:1025-1037(1987)

Sato M.
Salivary gland tumors.
(In) Human cell culture. Vol. 1. Cancer Cell Lines part 1; Masters J.R.W., Palsson B.O. (eds.); pp.161-178; Kluwer Academic Publishers; New York (1999)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

PubMed=29923277; DOI=10.1111/odi.12920
Lin L.-C., Elkashty O., Ramamoorthi M., Trinh N., Liu Y.-N., Sunavala-Dossabhoy G., Pranzatelli T., Michael D.G., Chivasso C., Perret J., Chiorini J.A., Delporte C., Tran S.D.
Cross-contamination of the human salivary gland HSG cell line with HeLa cells: a STR analysis study.
Oral Dis. 24:1477-1483(2018)

Cell line collections (Providers) JCRB; CHB0001 - Discontinued
Biological sample resources BioSample; SAMN03151716
BioSample; SAMN03471294
Encyclopedic resources Wikidata; Q54896488
Gene expression databases GEO; GSM1132848
GEO; GSM1132849
GEO; GSM1132850
GEO; GSM1132851
GEO; GSM1132856
GEO; GSM1132857
GEO; GSM1132858
GEO; GSM1132859
GEO; GSM1132860
GEO; GSM1132861
Polymorphism and mutation databases Cosmic; 974318
Entry history
Entry creation06-Jun-2012
Last entry update05-Oct-2023
Version number19