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Cellosaurus K562 eGFP-HMGB1 (CVCL_AW25)

[Text version]
Cell line name K562 eGFP-HMGB1
Accession CVCL_AW25
Resource Identification Initiative To cite this cell line use: K562 eGFP-HMGB1 (RRID:CVCL_AW25)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; 4983; HMGB1.
Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (from parent cell line).
Disease Blast phase chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C9110)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0004 (K-562)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line
Cross-references
Biological sample resources ENCODE; ENCBS332OKQ
ENCODE; ENCBS772IOG
Encyclopedic resources Wikidata; Q54899324
Entry history
Entry creation02-May-2016
Last entry update10-Sep-2024
Version number16