ID   MUG-CC1
AC   CVCL_AV05
SY   Medical University of Graz-Clivus Chordoma 1
DR   ATCC; CRL-3327
DR   cancercelllines; CVCL_AV05
DR   DSMZ; ACC-957
DR   GEO; GSM2495970
DR   GEO; GSM2495971
DR   GEO; GSM2495972
DR   Wikidata; Q54907054
RX   PubMed=27072875;
RX   PubMed=28515451;
WW   https://www.chordomafoundation.org/researchers/disease-models/mug-cc1/
CC   Doubling time: 109.16 +- 18.79 hours (PubMed=27072875); ~12 days (ATCC=CRL-3327); ~7 days (DSMZ=ACC-957); 15 days (Chordoma Foundation).
CC   HLA typing: A*24 (Chordoma Foundation).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro72Arg (c.215C>G); ClinVar=VCV000012351; Zygosity=Unspecified (PubMed=28515451).
CC   Omics: CNV analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Bone, cranium, clivus; UBERON=UBERON_0004108.
ST   Source(s): DSMZ=ACC-957; PubMed=27072875
ST   Amelogenin: X
ST   CSF1PO: 11
ST   D13S317: 12 (DSMZ=ACC-957)
ST   D13S317: 12,13 (PubMed=27072875)
ST   D16S539: 9,14 (PubMed=27072875)
ST   D16S539: 14 (DSMZ=ACC-957)
ST   D18S51: 12
ST   D19S433: 15
ST   D21S11: 28
ST   D2S1338: 17
ST   D3S1358: 16
ST   D5S818: 11,12
ST   D7S820: 8,11
ST   D8S1179: 13,15
ST   FGA: 23
ST   Penta D: 13
ST   Penta E: 10
ST   TH01: 9.3
ST   TPOX: 8,11
ST   vWA: 16,18
DI   NCIt; C5412; Clivus chordoma
DI   ORDO; Orphanet_178; Chordoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_DE11 ! MUG-CC1-LCL
SX   Male
AG   72Y
CA   Cancer cell line
DT   Created: 02-05-16; Last updated: 19-12-24; Version: 19
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RX   PubMed=27072875; DOI=10.1038/srep24195; PMCID=PMC4829844;
RA   Gellner V., Tomazic P.V., Lohberger B., Meditz K., Heitzer E.,
RA   Mokry M., Koele W., Leithner A., Liegl-Atzwanger B., Rinner B.;
RT   "Establishment of clival chordoma cell line MUG-CC1 and lymphoblastoid
RT   cells as a model for potential new treatment strategies.";
RL   Sci. Rep. 6:24195-24195(2016).
//
RX   PubMed=28515451; DOI=10.1038/s41598-017-02174-5; PMCID=PMC5435709;
RA   Jager D., Barth T.F.E., Bruderlein S., Scheuerle A., Rinner B.,
RA   von Witzleben A., Lechel A., Meyer P., Mayer-Steinacker R., von Baer A.,
RA   Schultheiss M., Wirtz C.R., Moller P., Mellert K.;
RT   "HOXA7, HOXA9, and HOXA10 are differentially expressed in clival and
RT   sacral chordomas.";
RL   Sci. Rep. 7:2032-2032(2017).
//