ID   HCEC 1CTR
AC   CVCL_AV03
SY   HCEC 1CT + shTP53; 1CTR
DR   Wikidata; Q54881863
RX   PubMed=21527559;
RX   PubMed=27047802;
CC   Knockout cell: Method=shRNA knockdown; HGNC; 11998; TP53.
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; 1773; CDK4.
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; 11730; TERT.
CC   Derived from site: In situ; Colon; UBERON=UBERON_0001155.
CC   Cell type: Epithelial cell of colon; CL=CL_0011108.
ST   Source(s): PubMed=27047802
ST   Amelogenin: X,Y
ST   CSF1PO: 10,12
ST   D13S317: 12,13
ST   D16S539: 10,11
ST   D21S11: 28
ST   D5S818: 11,14
ST   D7S820: 9,11
ST   TH01: 9.3
ST   TPOX: 11
ST   vWA: 16,18
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_AQ45 ! HCEC 1CT
SX   Male
AG   54Y
CA   Telomerase immortalized cell line
DT   Created: 02-05-16; Last updated: 10-09-24; Version: 7
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RX   PubMed=21527559; DOI=10.1158/0008-5472.CAN-11-0794; PMCID=PMC3326261;
RA   Eskiocak U., Kim S.B., Ly P., Roig A.I., Biglione S., Komurov K.,
RA   Cornelius C., Wright W.E., White M.A., Shay J.W.;
RT   "Functional parsing of driver mutations in the colorectal cancer
RT   genome reveals numerous suppressors of anchorage-independent growth.";
RL   Cancer Res. 71:4359-4365(2011).
//
RX   PubMed=27047802; DOI=10.3389/fcimb.2016.00034; PMCID=PMC4803749;
RA   Graillot V., Dormoy I., Dupuy J., Shay J.W., Huc L., Mirey G.,
RA   Vignard J.;
RT   "Genotoxicity of cytolethal distending toxin (CDT) on isogenic human
RT   colorectal cell lines: potential promoting effects for colorectal
RT   carcinogenesis.";
RL   Front. Cell. Infect. Microbiol. 6:34.1-34.13(2016).
//