Cellosaurus logo
expasy logo

Cellosaurus SK-HEP-1-FIX (CVCL_AU01)

[Text version]
Cell line name SK-HEP-1-FIX
Synonyms SK-Hep-1-FIX
Accession CVCL_AU01
Resource Identification Initiative To cite this cell line use: SK-HEP-1-FIX (RRID:CVCL_AU01)
Comments Problematic cell line: Misclassified. Parent cell line (SK-HEP-1) was originally described as originating from an adenocarcinoma of liver and thus classified as hepatocellular carcinoma. Later studies show that it most probably has arisen from endothelial cells.
Population: Caucasian.
Karyotypic information: Has lost chromosome Y (from parent cell line).
Transfected with: HGNC; 3551; F9.
Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Cell type: Endothelial cell; CL=CL_0000115.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
Disease Liver and intrahepatic bile duct epithelial neoplasm (NCIt: C7106)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0525 (SK-HEP-1)
Sex of cell Male
Age at sampling 52Y
Category Cancer cell line

PubMed=26802680; DOI=10.1016/j.pep.2015.11.023
de Sousa Bomfim A., Cristina Correa de Freitas M., Picanco-Castro V., de Abreu-Neto M.S., Swiech K., Covas D.T., de Sousa Russo E.M.
Human cell lines: a promising alternative for recombinant FIX production.
Protein Expr. Purif. 121:149-156(2016)

Cell line databases/resources cancercelllines; CVCL_AU01
Encyclopedic resources Wikidata; Q54953667
Entry history
Entry creation02-May-2016
Last entry update05-Oct-2023
Version number14