DR   IARC_TP53; 23823
DR   Wikidata; Q54954483
RX   DOI=10.1159/000407025;
RX   PubMed=11507071;
RX   PubMed=24792489;
CC   Problematic cell line: Probably contaminated. The STR profile is identical to that of the SK-N-AS cell line. Originally thought to originate from a neuroblastoma but the sex and age of the patient has not been reported.
CC   From: Memorial Sloan Kettering Cancer Center; New York; USA.
CC   Population: Caucasian.
CC   Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
ST   Source(s): COG
ST   Amelogenin: X
ST   CSF1PO: 10,12
ST   D13S317: 9
ST   D16S539: 14
ST   D18S51: 14,15
ST   D19S433: 12,14
ST   D21S11: 32.2,33.2
ST   D2S1338: 17,24
ST   D3S1358: 14
ST   D5S818: 11,12
ST   D7S820: 11,13
ST   D8S1179: 13,14
ST   FGA: 20,22
ST   TH01: 9.3
ST   TPOX: 11,12
ST   vWA: 16,17
DI   NCIt; C3270; Neuroblastoma
DI   ORDO; Orphanet_635; Neuroblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1700 ! SK-N-AS
SX   Female
AG   6Y
CA   Cancer cell line
DT   Created: 02-05-16; Last updated: 29-06-23; Version: 11
RX   DOI=10.1159/000407025;
RA   Helson L., Verma M., Helson C.;
RT   "Vitamin E and human neuroblastoma.";
RL   (In) Modulation and mediation of cancer by vitamins; Meyskens F.L., Prasad K.N. (eds.); pp.258-265; Karger; Basel (1983).
RX   PubMed=11507071;
RA   Keshelava N., Zuo J.J., Chen P., Waidyaratne S.N., Luna M.C.,
RA   Gomer C.J., Triche T.J., Reynolds C.P.;
RT   "Loss of p53 function confers high-level multidrug resistance in
RT   neuroblastoma cell lines.";
RL   Cancer Res. 61:6185-6193(2001).
RX   PubMed=24792489; DOI=10.1007/s11060-014-1456-8;
RA   Farooqi A.S., Dagg R.A., Choi L.M.R., Shay J.W., Reynolds C.P.,
RA   Lau L.M.S.;
RT   "Alternative lengthening of telomeres in neuroblastoma cell lines is
RT   associated with a lack of MYCN genomic amplification and with p53
RT   pathway aberrations.";
RL   J. Neurooncol. 119:17-26(2014).