ID   HCEC 2CT
AC   CVCL_AQ47
SY   Human Colonic Epithelial Cells 2 transduced with CDK4 and Telomerase; 2CT
DR   EFO; EFO_0009499
DR   Wikidata; Q54881865
RX   PubMed=19962984;
RX   PubMed=21527559;
CC   Genetic integration: Method=Transduction; Gene=HGNC; 1773; CDK4.
CC   Genetic integration: Method=Transduction; Gene=HGNC; 11730; TERT.
CC   Derived from site: In situ; Colon; UBERON=UBERON_0001155.
CC   Cell type: Epithelial cell of colon; CL=CL_0011108.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   52Y
CA   Telomerase immortalized cell line
DT   Created: 02-05-16; Last updated: 10-09-24; Version: 7
//
RX   PubMed=19962984; DOI=10.1053/j.gastro.2009.11.052;
RA   Roig A.I., Eskiocak U., Hight S.K., Kim S.B., Delgado O., Souza R.F.,
RA   Spechler S.J., Wright W.E., Shay J.W.;
RT   "Immortalized epithelial cells derived from human colon biopsies
RT   express stem cell markers and differentiate in vitro.";
RL   Gastroenterology 138:1012-1021.e215(2010).
//
RX   PubMed=21527559; DOI=10.1158/0008-5472.CAN-11-0794; PMCID=PMC3326261;
RA   Eskiocak U., Kim S.B., Ly P., Roig A.I., Biglione S., Komurov K.,
RA   Cornelius C., Wright W.E., White M.A., Shay J.W.;
RT   "Functional parsing of driver mutations in the colorectal cancer
RT   genome reveals numerous suppressors of anchorage-independent growth.";
RL   Cancer Res. 71:4359-4365(2011).
//