ID   CHLA-06-ATRT
AC   CVCL_AQ42
SY   CHLA06ATRT; CHLA-06
DR   ATCC; CRL-3038
DR   cancercelllines; CVCL_AQ42
DR   Cell_Model_Passport; SIDM01550
DR   DepMap; ACH-001028
DR   Wikidata; Q54812146
RX   PubMed=24300787;
RX   PubMed=25211508;
RX   PubMed=25246426;
RX   PubMed=25638158;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.His178Asp (c.532C>G); ClinVar=VCV000482223; Zygosity=Unspecified (DepMap=ACH-001028).
CC   Omics: Deep exome analysis.
CC   Derived from site: In situ; Brain, cerebellum; UBERON=UBERON_0002037.
ST   Source(s): ATCC=CRL-3038
ST   Amelogenin: X
ST   CSF1PO: 11
ST   D13S317: 13,14
ST   D16S539: 11,12
ST   D5S818: 11
ST   D7S820: 11,13
ST   TH01: 7
ST   TPOX: 12
ST   vWA: 16
DI   NCIt; C6906; Atypical teratoid/rhabdoid tumor
DI   ORDO; Orphanet_99966; Atypical teratoid rhabdoid tumor
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   4M
CA   Cancer cell line
DT   Created: 02-05-16; Last updated: 02-05-24; Version: 13
//
RX   PubMed=24300787; DOI=10.1158/1078-0432.CCR-13-2053;
RA   Erdreich-Epstein A., Robison N., Ren X.-H., Zhou H., Xu J.-Y.,
RA   Davidson T.B., Schur M., Gilles F.H., Ji L.-Y., Malvar J.,
RA   Shackleford G.M., Margol A.S., Krieger M.D., Judkins A.R., Jones D.T.W.,
RA   Pfister S.M., Kool M., Sposto R., Asgharzadeh S.;
RT   "PID1 (NYGGF4), a new growth-inhibitory gene in embryonal brain tumors
RT   and gliomas.";
RL   Clin. Cancer Res. 20:827-836(2014).
//
RX   PubMed=25211508; DOI=10.1002/jcb.24976;
RA   Xu J., Margol A.S., Asgharzadeh S., Erdreich-Epstein A.;
RT   "Pediatric brain tumor cell lines.";
RL   J. Cell. Biochem. 116:218-224(2015).
//
RX   PubMed=25246426; DOI=10.1093/neuonc/nou229;
RA   Chakravadhanula M., Hampton C.N., Chodavadia P., Ozols V., Zhou L.,
RA   Catchpoole D., Xu J.-Y., Erdreich-Epstein A., Bhardwaj R.D.;
RT   "Wnt pathway in atypical teratoid rhabdoid tumors.";
RL   Neuro-oncol. 17:526-535(2015).
//
RX   PubMed=25638158; DOI=10.18632/oncotarget.3078;
RA   Weingart M.F., Roth J.J., Hutt-Cabezas M., Busse T.M., Kaur H.,
RA   Price A., Maynard R., Rubens J., Taylor I.C., Mao X.-G., Xu J.-Y.,
RA   Kuwahara Y., Allen S.J., Erdreich-Epstein A., Weissman B.E., Orr B.A.,
RA   Eberhart C.G., Biegel J.A., Raabe E.H.;
RT   "Disrupting LIN28 in atypical teratoid rhabdoid tumors reveals the
RT   importance of the mitogen activated protein kinase pathway as a
RT   therapeutic target.";
RL   Oncotarget 6:3165-3177(2015).
//