ID   COG-N-415
AC   CVCL_AQ23
SY   COGN415
DR   cancercelllines; CVCL_AQ23
DR   GEO; GSM2371224
DR   GEO; GSM4104571
DR   GEO; GSM4104572
DR   GEO; GSM4104624
DR   GEO; GSM4104625
DR   GEO; GSM4105303
DR   GEO; GSM4105304
DR   GEO; GSM4105305
DR   GEO; GSM4105306
DR   GEO; GSM4105307
DR   Wikidata; Q54814023
RX   PubMed=24792489;
RX   PubMed=28340497;
RX   PubMed=28350380;
CC   Doubling time: 50 hours (COG).
CC   Sequence variation: Mutation; HGNC; HGNC:427; ALK; Simple; p.Phe1174Leu (c.3522C>A); ClinVar=VCV000217852; Zygosity=Unspecified (PubMed=28350380).
CC   Omics: Chromatin accessibility by ATAC-seq.
CC   Omics: H3K27ac ChIP-seq epigenome analysis.
CC   Omics: H3K27me3 ChIP-seq epigenome analysis.
CC   Omics: H3K4me1 ChIP-seq epigenome analysis.
CC   Omics: H3K4me3 ChIP-seq epigenome analysis.
CC   Omics: Transcriptome analysis by RNAseq.
ST   Source(s): COG
ST   Amelogenin: X
ST   CSF1PO: 10,11
ST   D13S317: 11,12
ST   D16S539: 11
ST   D18S51: 12,15
ST   D19S433: 14,15
ST   D21S11: 28,29
ST   D2S1338: 19,21
ST   D3S1358: 14,15
ST   D5S818: 11
ST   D7S820: 9,10
ST   D8S1179: 11,13,14
ST   FGA: 19,22
ST   TH01: 7,8
ST   TPOX: 11
ST   vWA: 17
DI   NCIt; C3270; Neuroblastoma
DI   ORDO; Orphanet_635; Neuroblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   2Y
CA   Cancer cell line
DT   Created: 02-05-16; Last updated: 19-12-24; Version: 13
//
RX   PubMed=24792489; DOI=10.1007/s11060-014-1456-8;
RA   Farooqi A.S., Dagg R.A., Choi L.M.R., Shay J.W., Reynolds C.P.,
RA   Lau L.M.S.;
RT   "Alternative lengthening of telomeres in neuroblastoma cell lines is
RT   associated with a lack of MYCN genomic amplification and with p53
RT   pathway aberrations.";
RL   J. Neurooncol. 119:17-26(2014).
//
RX   PubMed=28340497; DOI=10.1002/ijc.30706;
RA   Lopez-Barcons L., Maurer B.J., Kang M.H., Reynolds C.P.;
RT   "P450 inhibitor ketoconazole increased the intratumor drug levels and
RT   antitumor activity of fenretinide in human neuroblastoma xenograft
RT   models.";
RL   Int. J. Cancer 141:405-413(2017).
//
RX   PubMed=28350380; DOI=10.1038/sdata.2017.33; PMCID=PMC5369315;
RA   Harenza J.L., Diamond M.A., Adams R.N., Song M.M., Davidson H.L.,
RA   Hart L.S., Dent M.H., Fortina P., Reynolds C.P., Maris J.M.;
RT   "Transcriptomic profiling of 39 commonly-used neuroblastoma cell
RT   lines.";
RL   Sci. Data 4:170033-170033(2017).
//