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Cellosaurus Py8119 (CVCL_AQ09)

[Text version]
Cell line name Py8119
Synonyms PY8119
Accession CVCL_AQ09
Resource Identification Initiative To cite this cell line use: Py8119 (RRID:CVCL_AQ09)
Comments Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03077; Murine polyomavirus (strain A2) (MPyV) middle T antigen (PyMT).
Transformant: NCBI_TaxID; 10636; Murine polyomavirus (strain A2) (MPyV).
Miscellaneous: STR profile from personal communication of Rodriguez-Tarduchy Segovia, Gemma.
Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
Disease Malignant neoplasms of the mouse mammary gland (NCIt: C21678)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6 MMTV-PyMT transgenic.
Hierarchy Children:
CVCL_E3IG (HyCyte Py8119-Luc)
Sex of cell Female
Age at sampling Adult
Category Cancer cell line
STR profile Source(s): Direct_author_submission

Markers:
Mouse STR 1-117
Mouse STR 1-219
Mouse STR 2-116
Mouse STR 3-214
Mouse STR 4-220.3
Mouse STR 5-517
Mouse STR 6-418
Mouse STR 6-715
Mouse STR 7-126,27.2
Mouse STR 8-116
Mouse STR 11-216
Mouse STR 12-117
Mouse STR 13-117
Mouse STR 15-322.3
Mouse STR 17-215,17
Mouse STR 18-316
Mouse STR 19-213
Mouse STR X-127

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Publications

PubMed=22531600; DOI=10.1186/bcr3174; PMCID=PMC3446402
Gibby K., You W.-K., Kadoya K., Helgadottir H., Young L.J.T., Ellies L.G., Chang Y.-C., Cardiff R.D., Stallcup W.B.
Early vascular deficits are correlated with delayed mammary tumorigenesis in the MMTV-PyMT transgenic mouse following genetic ablation of the NG2 proteoglycan.
Breast Cancer Res. 14:R67.1-R67.20(2012)

PubMed=24368187; DOI=10.1016/j.canlet.2013.12.018; PMCID=PMC3947668
Biswas T., Gu X., Yang J.-H., Ellies L.G., Sun L.-Z.
Attenuation of TGF-beta signaling supports tumor progression of a mesenchymal-like mammary tumor cell line in a syngeneic murine model.
Cancer Lett. 346:129-138(2014)

Cross-references
Cell line collections (Providers) ATCC; CRL-3278
Encyclopedic resources Wikidata; Q54948762
Entry history
Entry creation02-May-2016
Last entry update10-Apr-2025
Version number10