Cellosaurus PD20 RV:D2 (CVCL_AK49)
| Cell line name | PD20 RV:D2 |
|---|---|
| Synonyms | PD.20hygro:RV; PD20-wtD2 |
| Accession | CVCL_AK49 |
| Resource Identification Initiative | To cite this cell line use: PD20 RV:D2 (RRID:CVCL_AK49) |
| Comments | Characteristics: Transfection of wildtype FANCD2 restores the full activity of the protein which is mutated in the parent cell line. Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:3585; FANCD2. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). Derived from site: In situ; Skin; UBERON=UBERON_0002097. Cell type: Fibroblast of skin; CL=CL_0002620. |
| Disease | Fanconi anemia, complementation group D2 (NCIt: C125706) Fanconi anemia (ORDO: Orphanet_84) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_G042 (GM16633) |
| Sex of cell | Male |
| Age at sampling | 7Y |
| Category | Transformed cell line |
| Web pages | http://www.ohsu.edu/research/fanconi-anemia/celllines.cfm |
| Publications | PubMed=12361951; DOI=10.1074/jbc.M207937200 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q54946782 |
| Entry history | |
| Entry creation | 02-May-2016 |
| Last entry update | 19-Dec-2024 |
| Version number | 14 |