ID   HSC 536N
AC   CVCL_AK36
SY   HSC-536N; HSC536N; HSC 536/N; HSC/536N; GM13021
DR   CLO; CLO_0013991
DR   BioSample; SAMN00802016
DR   Coriell; GM13021
DR   Wikidata; Q54896373
RX   PubMed=8822951;
RX   PubMed=11926188;
CC   Sequence variation: Mutation; HGNC; HGNC:3584; FANCC; Simple; p.Leu554Pro (c.1661T>C); ClinVar=VCV000012043; Zygosity=Unspecified (Coriell=GM13021).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
DI   NCIt; C125704; Fanconi anemia, complementation group C
DI   ORDO; Orphanet_84; Fanconi anemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_G045 ! HSC 536
SX   Male
AG   5Y
CA   Transformed cell line
DT   Created: 02-05-16; Last updated: 19-12-24; Version: 14
//
RX   PubMed=8822951; DOI=10.1182/blood.V88.6.2298.bloodjournal8862298;
RA   Marathi U.K., Howell S.R., Ashmun R.A., Brent T.P.;
RT   "The Fanconi anemia complementation group C protein corrects DNA
RT   interstrand cross-link-specific apoptosis in HSC536N cells.";
RL   Blood 88:2298-2305(1996).
//
RX   PubMed=11926188; DOI=10.1182/blood.V99.7.2627a;
RA   Rutherford T.R., Myatt N.E., Gibson F.M., Clarke A.A.;
RT   "The Fanconi anemia cell line HSC536N is not sensitive to
RT   interferon-gamma and does not cleave PARP in response to FAS-mediated
RT   cell killing.";
RL   Blood 99:2627-2628(2002).
//