Cellosaurus cell line MOC-L3 (CVCL

Cross-references
Cell line name	MOC-L3
Synonyms	Mouse Oral Carcinoma-Line 3
Accession	CVCL_A9X5
Resource Identification Initiative	To cite this cell line use: MOC-L3 (RRID:CVCL_A9X5)
Comments	Doubling time: 20.3 hours (PubMed=30922255). Genetic integration: Method=Transgenic mouse; Gene=MGI; MGI:2676887; Mir211. Genetic integration: Method=Transgenic mouse; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP). Transformant: ChEBI; CHEBI_16907; 4-nitroquinoline N-oxide (4NQO). Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
Sequence variations	Mutation; MGI; MGI:98834; Trp53; Simple; p.Gly241Glu (c.722G>A); Zygosity=Unspecified (PubMed=30922255).
Disease	Squamous cell carcinoma of the mouse oral cavity (NCIt: C23049)
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090) Breed/subspecies: C57BL/6 K14-EGFP-miR-211 transgenic.
Sex of cell	Sex unspecified
Age at sampling	22-28W
Category	Cancer cell line
Publications	PubMed=30922255; DOI=10.1186/s12885-019-5486-7; PMCID=PMC6440159 Chen Y.-F., Liu C.-J., Lin L.-H., Chou C.-H., Yeh L.-Y., Lin S.-C., Chang K.-W. Establishing of mouse oral carcinoma cell lines derived from transgenic mice and their use as syngeneic tumorigenesis models. BMC Cancer 19:281.1-281.11(2019)
Cell line collections (Providers)	BCRC; 60618
Encyclopedic resources	Wikidata; Q102114549
Entry history
Entry creation	29-Oct-2020
Last entry update	19-Dec-2024
Version number	7