Cellosaurus logo
expasy logo

Cellosaurus MOC-L1 (CVCL_A9X3)

[Text version]
Cell line name MOC-L1
Synonyms Mouse Oral Carcinoma-Line 1
Accession CVCL_A9X3
Resource Identification Initiative To cite this cell line use: MOC-L1 (RRID:CVCL_A9X3)
Comments Characteristics: Tumorigenic in syngeneic mice and also possesses a competence for neck dissemination.
Doubling time: 24.7 hours (PubMed=30922255).
Genetic integration: Method=Transgenic mouse; Gene=MGI; MGI:2676887; Mir211.
Genetic integration: Method=Transgenic mouse; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Transformant: ChEBI; CHEBI_16907; 4-nitroquinoline N-oxide (4NQO).
Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
Sequence variations
  • Mutation; MGI; MGI:98834; Trp53; Simple; p.Thr122Asn (c.365_366CG>AT); Zygosity=Unspecified (PubMed=30922255).
Disease Squamous cell carcinoma of the mouse oral cavity (NCIt: C23049)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6 K14-EGFP-miR-211 transgenic.
Sex of cell Sex unspecified
Age at sampling 22-28W
Category Cancer cell line
Publications

PubMed=30922255; DOI=10.1186/s12885-019-5486-7; PMCID=PMC6440159
Chen Y.-F., Liu C.-J., Lin L.-H., Chou C.-H., Yeh L.-Y., Lin S.-C., Chang K.-W.
Establishing of mouse oral carcinoma cell lines derived from transgenic mice and their use as syngeneic tumorigenesis models.
BMC Cancer 19:281.1-281.11(2019)

Cross-references
Cell line collections (Providers) BCRC; 60616
Encyclopedic resources Wikidata; Q102114547
Entry history
Entry creation29-Oct-2020
Last entry update19-Dec-2024
Version number7