Cellosaurus logo
expasy logo

Cellosaurus CTSC#510 (CVCL_A9WY)

[Text version]
Cell line name CTSC#510
Synonyms CRC-SC#510
Accession CVCL_A9WY
Resource Identification Initiative To cite this cell line use: CTSC#510 (RRID:CVCL_A9WY)
Comments Group: Cancer stem cell line.
From: Sant Andrea Hospital; Rome; Italy.
Microsatellite instability: Instable (MSI-high) (PubMed=33128777).
Derived from site: In situ; Colon, proximal; UBERON=UBERON_0008972.
Sequence variations
  • Mutation; HGNC; HGNC:583; APC; Simple; p.Gln1752Ter (c.5254C>T); Zygosity=Unspecified (PubMed=33128777).
  • Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Thr41Ile (c.122C>T); ClinVar=VCV000017587; Zygosity=Unspecified (PubMed=33128777).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000177777; Zygosity=Unspecified (PubMed=33128777).
  • Mutation; HGNC; HGNC:6770; SMAD4; Simple; p.Asn107Metfs*3 (c.320delA) (c.316delA); ClinVar=VCV001728912; Zygosity=Unspecified (PubMed=33128777).
  • Mutation; HGNC; HGNC:6770; SMAD4; Simple; p.Arg361His (c.1082G>A); ClinVar=VCV000024832; Zygosity=Unspecified (PubMed=33128777).
  • Mutation; HGNC; HGNC:11641; TCF7L2; Simple; p.Asp91Val (c.272A>T); Zygosity=Unspecified (PubMed=33128777).
  • Mutation; HGNC; HGNC:11641; TCF7L2; Simple; p.Met411Thr (c.1232T>C); Zygosity=Unspecified (PubMed=33128777).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu388Lys (c.1162G>A); Zygosity=Unspecified (PubMed=33128777).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser392Ter (c.1175C>A); dbSNP=rs769664911; Zygosity=Unspecified (PubMed=33128777).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ter394Aspext*28 (c.1180_1182insGAC); Zygosity=Unspecified (PubMed=33128777).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 73Y
Category Cancer cell line
STR profile Source(s): PubMed=33128777

Markers:
AmelogeninX
CSF1PO10,11
D5S81812,13
D7S82010,11
D13S3179,12
D16S5399,12
TH018,9
TPOX8,9
vWA18,20

Run an STR similarity search on this cell line
Publications

PubMed=33128777; DOI=10.1002/ijc.33370; PMCID=PMC7894552
Visconti P., Parodi F., Parodi B., Casarino L., Romano P., Buccarelli M., Pallini R., D'Alessandris Q.G., Montori A., Pilozzi E., Ricci-Vitiani L.
Short tandem repeat profiling for the authentication of cancer stem-like cells.
Int. J. Cancer 148:1489-1498(2021)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A9WY
Encyclopedic resources Wikidata; Q102113755
Entry history
Entry creation29-Oct-2020
Last entry update19-Dec-2024
Version number8