Cellosaurus cell line FFF-028 (CVCL

Cross-references
Cell line name	FFF-028
Synonyms	FFF0112010
Accession	CVCL_A9P8
Resource Identification Initiative	To cite this cell line use: FFF-028 (RRID:CVCL_A9P8)
Comments	Derived from site: In situ; Skin; UBERON=UBERON_0002097. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:18618; LRRK2; Simple; p.Gly2019Ser (c.6055G>A); ClinVar=VCV000001940; Zygosity=Homozygous (PubMed=22666358).
Disease	Parkinson disease 8, autosomal dominant (NCIt: C198605) Hereditary late-onset Parkinson disease (ORDO: Orphanet_411602)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	68Y
Category	Finite cell line
Publications	PubMed=22666358; DOI=10.1371/journal.pone.0037467; PMCID=PMC3359730 Cartelli D., Goldwurm S., Casagrande F., Pezzoli G., Cappelletti G. Microtubule destabilization is shared by genetic and idiopathic Parkinson's disease patient fibroblasts. PLoS ONE 7:E37467-E37467(2012) PubMed=23075850; DOI=10.1038/nature11557; PMCID=PMC3504651 Liu G.-H., Qu J., Suzuki K., Nivet E., Li M., Montserrat N., Yi F., Xu X.-L., Ruiz S., Zhang W.-Q., Wagner U., Kim A., Ren B., Li Y., Goebl A., Kim J., Soligalla R.D., Dubova I., Thompson J., Yates J.R. 3rd, Esteban C.R., Sancho-Martinez I., Izpisua Belmonte J.C. Progressive degeneration of human neural stem cells caused by pathogenic LRRK2. Nature 491:603-607(2012)
Encyclopedic resources	Wikidata; Q102113821
Entry history
Entry creation	29-Oct-2020
Last entry update	19-Dec-2024
Version number	7