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Cellosaurus SW620-Luc2-tdT (CVCL_A9MK)

[Text version]
Cell line name SW620-Luc2-tdT
Accession CVCL_A9MK
Resource Identification Initiative To cite this cell line use: SW620-Luc2-tdT (RRID:CVCL_A9MK)
Comments Population: Caucasian.
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Firefly luciferase (Note=With optimized codon usage for mammalian expression).
Genetic integration: Method=Transduction; Gene=FPbase; PGG5S; tdTomato (Note=Bright red fluorescent protein derived from drFP583 (DsRed)).
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Mutation; HGNC; 583; APC; Simple; p.Gln1338Ter (c.4012C>T); ClinVar=VCV000000801; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Pro309Ser (c.925C>T); ClinVar=VCV000458575; Zygosity=Heterozygous (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0547 (SW620)
Sex of cell Male
Age at sampling 51Y
Category Cancer cell line
STR profile Source(s): CCRID=1101HUM-PUMC000840

Markers:
AmelogeninX
CSF1PO13,14
D2S133817,24
D3S135815
D5S81813
D7S8208
D8S117913
D13S31712
D16S53913
D18S5113
D19S43313
D21S1130,30.2
FGA24
TH018
TPOX11
vWA16

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Cross-references
Cell line databases/resources cancercelllines; CVCL_A9MK
CCRID; 1101HUM-PUMC000840
Encyclopedic resources Wikidata; Q108821349
Entry history
Entry creation23-Sep-2021
Last entry update10-Sep-2024
Version number8