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Cellosaurus COLO 205-Luc2-tdT (CVCL_A9DH)

[Text version]
Cell line name COLO 205-Luc2-tdT
Accession CVCL_A9DH
Resource Identification Initiative To cite this cell line use: COLO 205-Luc2-tdT (RRID:CVCL_A9DH)
Comments Population: Caucasian.
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Firefly luciferase (Note=With optimized codon usage for mammalian expression).
Genetic integration: Method=Transduction; Gene=FPbase; PGG5S; tdTomato (Note=Bright red fluorescent protein derived from drFP583 (DsRed)).
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; HGNC:583; APC; Simple; p.Thr1556Asnfs*3 (c.4666dupA) (c.4666_4667insA); ClinVar=VCV000428112; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Asn287Ser (c.860A>G); ClinVar=VCV000133954; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr103fs*37 (c.308_321delTGTGTAACAGTTCC); Zygosity=Homozygous (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0218 (COLO 205)
Sex of cell Male
Age at sampling 70Y
Category Cancer cell line
Cross-references
Cell line databases/resources cancercelllines; CVCL_A9DH
CCRID; 1101HUM-PUMC000848
Encyclopedic resources Wikidata; Q108820076
Entry history
Entry creation23-Sep-2021
Last entry update19-Dec-2024
Version number8