Cellosaurus logo
expasy logo

Cellosaurus RPMI-8226-Luc2-tdT (CVCL_A9DA)

[Text version]
Cell line name RPMI-8226-Luc2-tdT
Accession CVCL_A9DA
Resource Identification Initiative To cite this cell line use: RPMI-8226-Luc2-tdT (RRID:CVCL_A9DA)
Comments Population: African American.
Characteristics: Produces IgG lambda (from parent cell line).
Genetic integration: Method=Transfection; Gene=UniProtKB; P08659; Firefly luciferase (Note=With optimized codon usage for mammalian expression).
Genetic integration: Method=Transfection; Gene=FPbase; PGG5S; tdTomato (Note=Bright red fluorescent protein derived from drFP583 (DsRed)).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Gene fusion; HGNC; 5722; IGKJ4 + HGNC; 5783; IGKV2-28; Name(s)=IGKV2-28-IGKJ4 (from parent cell line).
  • Gene fusion; HGNC; 5865; IGLJ3 + HGNC; 5888; IGLV2-14; Name(s)=IGLV2-14-IGLJ3 (from parent cell line).
  • Mutation; HGNC; 3236; EGFR; Simple; p.Thr751Ile (c.2252C>T); ClinVar=VCV000177773; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Ala (c.35G>C); ClinVar=VCV000045122; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Glu285Lys (c.853G>A); ClinVar=VCV000420133; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 12033; TRAF3; Simple; p.Lys191Leufs*60; Zygosity=Unspecified (from parent cell line).
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0014 (RPMI-8226)
Sex of cell Male
Age at sampling 61Y
Category Cancer cell line
STR profile Source(s): CCRID=1101HUM-PUMC000852

Markers:
AmelogeninX,Y
CSF1PO12
D2S133820
D3S135816,17
D5S81811,13
D7S8209,10
D8S117912,13
D13S31711
D16S5399
D18S5115,19
D19S43313.2,14
D21S1128,29
FGA19
TH018
TPOX8,11
vWA16,18

Run an STR similarity search on this cell line
Cross-references
Cell line databases/resources cancercelllines; CVCL_A9DA
CCRID; 1101HUM-PUMC000852
Encyclopedic resources Wikidata; Q108821249
Entry history
Entry creation23-Sep-2021
Last entry update10-Sep-2024
Version number8