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Cellosaurus Detroit 98/Apt (CVCL_A9AR)

[Text version]
Cell line name Detroit 98/Apt
Synonyms D98/Apt
Accession CVCL_A9AR
Resource Identification Initiative To cite this cell line use: Detroit 98/Apt (RRID:CVCL_A9AR)
Comments Problematic cell line: Contaminated. Grand-parent cell line (Detroit 98) has been shown to be a HeLa derivative.
Population: African American.
Selected for resistance to: ChEBI; CHEBI:22526; 4-aminofolic acid (Aminopterin).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_8192 (Detroit 98S)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line

PubMed=13980043; DOI=10.1073/pnas.48.12.2026
Szybalska E.H., Szybalski W.
Genetics of human cell line. IV. DNA-mediated heritable transformation of a biochemical trait.
Proc. Natl. Acad. Sci. U.S.A. 48:2026-2034(1962)

Encyclopedic resources Wikidata; Q108820149
Entry history
Entry creation23-Sep-2021
Last entry update05-Oct-2023
Version number5