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Cellosaurus LN229/CD20 (CVCL_A8V5)

[Text version]
Cell line name LN229/CD20
Accession CVCL_A8V5
Resource Identification Initiative To cite this cell line use: LN229/CD20 (RRID:CVCL_A8V5)
Comments Population: Caucasian.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:7315; MS4A1 (Note=With a N-terminal GVAMPGAEDDVV = PA-tag).
Genetic integration: Method=Transfection; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
Derived from site: In situ; Brain, right frontal parieto-occipital cortex.
Sequence variations
  • Mutation; HGNC; HGNC:6597; LIFR; Simple; p.Pro1060Ala (c.3178C>G); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9811; RAD21; Simple; p.Gln132Ter (c.394C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro98Leu (c.293C>T); ClinVar=VCV000528236; Zygosity=Homozygous (from parent cell line).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0393 (LN-229)
Sex of cell Female
Age at sampling 60Y
Category Cancer cell line
Publications

PubMed=32667234; DOI=10.1089/mab.2020.0015
Furusawa Y., Kaneko M.K., Kato Y.
Establishment of an anti-CD20 monoclonal antibody (C20Mab-60) for immunohistochemical analyses.
Monoclon. Antib. Immunodiagn. Immunother. 39:112-116(2020)

PubMed=32724441; DOI=10.3892/ol.2020.11753; PMCID=PMC7377059
Furusawa Y., Kaneko M.K., Kato Y.
Establishment of C20Mab-11, a novel anti-CD20 monoclonal antibody, for the detection of B cells.
Oncol. Lett. 20:1961-1967(2020)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A8V5
Encyclopedic resources Wikidata; Q102114467
Entry history
Entry creation29-Oct-2020
Last entry update19-Dec-2024
Version number9