ID   JR1Nmyc9
AC   CVCL_A8SK
DR   Wikidata; Q108820565
RX   PubMed=10933967;
CC   Characteristics: Expresses MYCN under the control of the CMV promoter (PubMed=10933967).
CC   Genetic integration: Method=Transfection; Gene=HGNC; 7559; MYCN.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: Metastatic; Lung; UBERON=UBERON_0002048.
DI   NCIt; C8971; Embryonal rhabdomyosarcoma
DI   ORDO; Orphanet_99757; Embryonal rhabdomyosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_J063 ! JR-1
SX   Female
AG   7Y
CA   Cancer cell line
DT   Created: 23-09-21; Last updated: 10-09-24; Version: 5
//
RX   PubMed=10933967; DOI=10.1006/mthe.2000.0064;
RA   Pawlik C.A., Iyengar R.V., Krull E.J., Mason S.E., Khanna R.,
RA   Harris L.C., Potter P.M., Danks M.K., Guichard S.M.;
RT   "Use of the ornithine decarboxylase promoter to achieve N-MYC-mediated
RT   overexpression of a rabbit carboxylesterase to sensitize neuroblastoma
RT   cells to CPT-11.";
RL   Mol. Ther. 1:457-463(2000).
//