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Cellosaurus JR1Nmyc6 (CVCL_A8SJ)

[Text version]
Cell line name JR1Nmyc6
Accession CVCL_A8SJ
Resource Identification Initiative To cite this cell line use: JR1Nmyc6 (RRID:CVCL_A8SJ)
Comments Characteristics: Expresses MYCN under the control of the CMV promoter (PubMed=10933967).
Genetic integration: Method=Transfection; Gene=HGNC; 7559; MYCN.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: Metastatic; Lung; UBERON=UBERON_0002048.
Disease Embryonal rhabdomyosarcoma (NCIt: C8971)
Embryonal rhabdomyosarcoma (ORDO: Orphanet_99757)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_J063 (JR-1)
Sex of cell Female
Age at sampling 7Y
Category Cancer cell line
Publications

PubMed=10933967; DOI=10.1006/mthe.2000.0064
Pawlik C.A., Iyengar R.V., Krull E.J., Mason S.E., Khanna R., Harris L.C., Potter P.M., Danks M.K., Guichard S.M.
Use of the ornithine decarboxylase promoter to achieve N-MYC-mediated overexpression of a rabbit carboxylesterase to sensitize neuroblastoma cells to CPT-11.
Mol. Ther. 1:457-463(2000)

PubMed=11306486
Iyengar R.V., Pawlik C.A., Krull E.J., Phelps D.A., Burger R.A., Harris L.C., Potter P.M., Danks M.K.
Use of a modified ornithine decarboxylase promoter to achieve efficient c-MYC- or N-MYC-regulated protein expression.
Cancer Res. 61:3045-3052(2001)

Cross-references
Encyclopedic resources Wikidata; Q108820564
Entry history
Entry creation23-Sep-2021
Last entry update10-Sep-2024
Version number5