ID   SJ-GBM3
AC   CVCL_A8SF
SY   SJ-G3
DR   cancercelllines; CVCL_A8SF
DR   IARC_TP53; 24986
DR   Wikidata; Q108821305
RX   CelloPub=CLPUB00738;
RX   PubMed=9802058;
RX   PubMed=10402232;
RX   PubMed=10933967;
RX   PubMed=11306486;
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser90Profs*33 (c.267delC); ClinVar=VCV000156515; Zygosity=Unspecified (PubMed=9802058).
CC   Derived from site: In situ; Brain; UBERON=UBERON_0000955.
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   12Y
CA   Cancer cell line
DT   Created: 23-09-21; Last updated: 19-12-24; Version: 6
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RX   CelloPub=CLPUB00738;
RA   Nitiss K.C.;
RT   "Oncogenic changes and induction of differentiation in pediatric
RT   astrocytic cell lines.";
RL   Thesis PhD (1997); University of Southern California Los Angeles; Los Angeles; USA.
//
RX   PubMed=9802058;
RA   McPake C.R., Tillman D.M., Poquette C.A., George E.O., Houghton J.A.,
RA   Harris L.C.;
RT   "Bax is an important determinant of chemosensitivity in pediatric
RT   tumor cell lines independent of Bcl-2 expression and p53 status.";
RL   Oncol. Res. 10:235-244(1998).
//
RX   PubMed=10402232; DOI=10.3892/ijo.15.2.237;
RA   Sharif T.R., Sharif M.;
RT   "Overexpression of protein kinase C epsilon in astroglial brain tumor
RT   derived cell lines and primary tumor samples.";
RL   Int. J. Oncol. 15:237-243(1999).
//
RX   PubMed=10933967; DOI=10.1006/mthe.2000.0064;
RA   Pawlik C.A., Iyengar R.V., Krull E.J., Mason S.E., Khanna R.,
RA   Harris L.C., Potter P.M., Danks M.K., Guichard S.M.;
RT   "Use of the ornithine decarboxylase promoter to achieve N-MYC-mediated
RT   overexpression of a rabbit carboxylesterase to sensitize neuroblastoma
RT   cells to CPT-11.";
RL   Mol. Ther. 1:457-463(2000).
//
RX   PubMed=11306486;
RA   Iyengar R.V., Pawlik C.A., Krull E.J., Phelps D.A., Burger R.A.,
RA   Harris L.C., Potter P.M., Danks M.K.;
RT   "Use of a modified ornithine decarboxylase promoter to achieve
RT   efficient c-MYC- or N-MYC-regulated protein expression.";
RL   Cancer Res. 61:3045-3052(2001).
//