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Cellosaurus CAP-CD63-tGFP-miRNA-493 (CVCL_A8SC)

[Text version]
Cell line name CAP-CD63-tGFP-miRNA-493
Accession CVCL_A8SC
Resource Identification Initiative To cite this cell line use: CAP-CD63-tGFP-miRNA-493 (RRID:CVCL_A8SC)
Comments Characteristics: Overexpresses CD63-turboGFP and MIR493. Transduced with a pStbl-CMV-bsd-CD63-tGFP vector and a pEGP-CMV-hsa-miRNA-493 vector.
Genetic integration: Method=Transduction; Gene=HGNC; 1692; CD63.
Genetic integration: Method=Transduction; Gene=HGNC; 32082; MIR493.
Genetic integration: Method=Transduction; Gene=FPbase; A315M; TurboGFP (Note=Green fluorescent protein from P.plumata).
Genetic integration: Method=Transduction; Gene=UniProtKB; P0C2P0; Aspergillus terreus blasticidin-S deaminase (Bsd).
Genetic integration: Method=Transduction; Gene=UniProtKB; P03281; Adenovirus 5 pIX.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
Transformant: NCBI_TaxID; 28285; Adenovirus 5 (Note=E1A/E1B).
Derived from site: In situ; Amniotic fluid; UBERON=UBERON_0000173.
Cell type: Amniocyte; CL=CL_0002323.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_A8RY (CAP-CD63-tGFP)
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=31461486; DOI=10.1371/journal.pone.0221679; PMCID=PMC6713437
Zeh N., Schneider H., Mathias S., Raab N., Kleemann M., Schmidt-Hertel S., Weis B., Wissing S., Strempel N., Handrick R., Otte K.
Human CAP cells represent a novel source for functional, miRNA-loaded exosome production.
PLoS ONE 14:E0221679-E0221679(2019)

Cross-references
Encyclopedic resources Wikidata; Q108819984
Entry history
Entry creation23-Sep-2021
Last entry update10-Sep-2024
Version number7