ID   MDS-L/GFP-N
AC   CVCL_A8QW
DR   cancercelllines; CVCL_A8QW
DR   Wikidata; Q108820888
RX   PubMed=11108571;
CC   Population: Japanese.
CC   Characteristics: Transduced with a 5'LTR-CMV-rsGFP-Neo-3'LTR construct.
CC   Sequence variation: Mutation; HGNC; HGNC:1833; CEBPA; Simple; p.Gln311Ter (c.931C>T); ClinVar=VCV000851673; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gly12Ala (c.35G>C); ClinVar=VCV000219097; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; c.672+1G>A; ClinVar=VCV000216078; Zygosity=Homozygous; Note=Splice donor mutation (from parent cell line).
CC   Genetic integration: Method=Transduction; Gene=FPbase; JYYJ1; rsEGFP (Note=rsGFP, red-shifted GFP).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
DI   NCIt; C3247; Myelodysplastic syndrome
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_A8QV ! MDS-L
SX   Male
AG   52Y
CA   Cancer cell line
DT   Created: 23-09-21; Last updated: 19-12-24; Version: 7
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RX   PubMed=11108571; DOI=10.1080/13684730050515787;
RA   Nakamura S., Ohnishi K., Yoshida H., Shinjo K., Takeshita A.,
RA   Tohyama K., Ohno R., Koide Y.;
RT   "Retrovirus-mediated gene transfer of granulocyte colony-stimulating
RT   factor receptor (G-CSFR) cDNA into MDS cells and induction of their
RT   differentiation by G-CSF.";
RL   Cytokines Cell. Mol. Ther. 6:61-70(2000).
//