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Cellosaurus MIN6-cl4 (CVCL_A8QH)

[Text version]
Cell line name MIN6-cl4
Synonyms MIN6.cl4; MIN6 clone 4
Accession CVCL_A8QH
Resource Identification Initiative To cite this cell line use: MIN6-cl4 (RRID:CVCL_A8QH)
Comments Characteristics: Retains glucose-stimulated insulin secretion even after long-term culture (PubMed=23560115).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Pancreas, islets of Langerhans; UBERON=UBERON_0000006.
Cell type: Pancreatic beta cell; CL=CL_0000169.
Disease Mouse insulinoma (NCIt: C34053)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6 IT6 transgenic.
Hierarchy Parent: CVCL_0431 (MIN6)
Sex of cell Sex unspecified
Age at sampling 13W
Category Transformed cell line
Publications

PubMed=23560115; DOI=10.1371/journal.pone.0061211; PMCID=PMC3616144
Yamato E., Tashiro F., Miyazaki J.-i.
Microarray analysis of novel candidate genes responsible for glucose-stimulated insulin secretion in mouse pancreatic beta cell line MIN6.
PLoS ONE 8:E61211-E61211(2013)

PubMed=33436850; DOI=10.1038/s41598-020-79992-7; PMCID=PMC7804151
Miyazaki S., Tashiro F., Tsuchiya T., Sasaki K., Miyazaki J.-i.
Establishment of a long-term stable beta-cell line and its application to analyze the effect of Gcg expression on insulin secretion.
Sci. Rep. 11:477-477(2021)

Cross-references
Encyclopedic resources Wikidata; Q108820933
Entry history
Entry creation23-Sep-2021
Last entry update29-Jun-2023
Version number4