ID   MCF-7 TTE-MBD2
AC   CVCL_A8P5
DR   cancercelllines; CVCL_A8P5
DR   GEO; GSM1322266
DR   GEO; GSM1322268
DR   GEO; GSM1322269
DR   GEO; GSM1388122
DR   GEO; GSM1388124
DR   GEO; GSM1388125
DR   GEO; GSM1388126
DR   GEO; GSM1388127
DR   Wikidata; Q102114501
RX   PubMed=24927503;
CC   Population: Caucasian.
CC   Characteristics: The transfected human MBD2 gene is N-terminally tagged with a Ty1-Ty1-ER (TTE) epitope tag.
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:6917; MBD2.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Omics: MBD2 ChIP-seq epigenome analysis.
CC   Omics: Pol2 ChIP-seq epigenome analysis.
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C4194; Invasive breast carcinoma of no special type
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0031 ! MCF-7
SX   Female
AG   69Y
CA   Cancer cell line
DT   Created: 29-10-20; Last updated: 19-12-24; Version: 9
//
RX   PubMed=24927503; DOI=10.1371/journal.pone.0099603; PMCID=PMC4057170;
RA   Menafra R., Brinkman A.B., Matarese F., Franci G., Bartels S.J.J.,
RA   Nguyen L., Shimbo T., Wade P.A., Hubner N.C., Stunnenberg H.G.;
RT   "Genome-wide binding of MBD2 reveals strong preference for highly
RT   methylated loci.";
RL   PLoS ONE 9:E99603-E99603(2014).
//