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Cellosaurus LCSBi007-A (CVCL_A8ME)

[Text version]
Cell line name LCSBi007-A
Synonyms ND27760-PARK1/SNCA-triplication-clone 2; ND27760-SNCA-triplication-clone 2; ND27760-SNCA3x clone 2; ND27760-clone 2
Accession CVCL_A8ME
Resource Identification Initiative To cite this cell line use: LCSBi007-A (RRID:CVCL_A8ME)
Comments From: Luxembourg Centre for Systems Biomedicine; Belvaux; Luxembourg.
Population: Caucasian.
Omics: Array-based CGH.
Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Gene amplification; HGNC; 11138; SNCA; Triplication; Zygosity=Heterozygous (PubMed=34826737).
Disease Parkinson disease 4, autosomal dominant (NCIt: C198604)
Hereditary late-onset Parkinson disease (ORDO: Orphanet_411602)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_F204 (ND27760)
Sex of cell Female
Age at sampling 55Y
Category Induced pluripotent stem cell
Publications

PubMed=34826737; DOI=10.1016/j.scr.2021.102600; PMCID=PMC9124237
Novak G., Finkbeiner S., Skibinski G., Skupin A.
Generation of two human induced pluripotent stem cell lines (iPSCs) with mutations of the alpha-synuclein (SNCA) gene associated with Parkinson's disease; the A53T mutation (LCSBi003) and a triplication of the SNCA gene (LCSBi007).
Stem Cell Res. 57:102600-102600(2021)

Cross-references
Cell line databases/resources hPSCreg; LCSBi007-A
Encyclopedic resources Wikidata; Q108820778
Entry history
Entry creation23-Sep-2021
Last entry update29-Jun-2023
Version number4