Cellosaurus cell line LCSBi007-A (CVCL

Cross-references
Cell line name	LCSBi007-A
Synonyms	ND27760-PARK1/SNCA-triplication-clone 2; ND27760-SNCA-triplication-clone 2; ND27760-SNCA3x clone 2; ND27760-clone 2
Accession	CVCL_A8ME
Resource Identification Initiative	To cite this cell line use: LCSBi007-A (RRID:CVCL_A8ME)
Comments	From: Luxembourg Centre for Systems Biomedicine; Belvaux; Luxembourg. Population: Caucasian. Omics: Array-based CGH. Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Gene amplification; HGNC; HGNC:11138; SNCA; Triplication; Zygosity=Heterozygous (PubMed=34826737).
Disease	Parkinson disease 4, autosomal dominant (NCIt: C198604) Hereditary late-onset Parkinson disease (ORDO: Orphanet_411602)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_F204 (ND27760)
Sex of cell	Female
Age at sampling	55Y
Category	Induced pluripotent stem cell
Publications	PubMed=34826737; DOI=10.1016/j.scr.2021.102600; PMCID=PMC9124237 Novak G., Finkbeiner S., Skibinski G., Skupin A. Generation of two human induced pluripotent stem cell lines (iPSCs) with mutations of the alpha-synuclein (SNCA) gene associated with Parkinson's disease; the A53T mutation (LCSBi003) and a triplication of the SNCA gene (LCSBi007). Stem Cell Res. 57:102600-102600(2021)
Cell line databases/resources	hPSCreg; LCSBi007-A
Encyclopedic resources	Wikidata; Q108820778
Entry history
Entry creation	23-Sep-2021
Last entry update	19-Dec-2024
Version number	5