Cellosaurus cell line LCSBi006-A (CVCL

Cross-references
Cell line name	LCSBi006-A
Synonyms	ND34267-LRRK2/PARK8-G2019S-clone 8; ND34267-LRRK2-clone 8; ND34267-clone 8; ND34267-8
Accession	CVCL_A8MD
Resource Identification Initiative	To cite this cell line use: LCSBi006-A (RRID:CVCL_A8MD)
Comments	From: Luxembourg Centre for Systems Biomedicine; Belvaux; Luxembourg. Population: Caucasian. Derived from site: In situ; Skin; UBERON=UBERON_0002097. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:18618; LRRK2; Simple; p.Gly2019Ser (c.6055G>A); ClinVar=VCV000001940; Zygosity=Heterozygous (PubMed=34736041).
Disease	Parkinson disease 8, autosomal dominant (NCIt: C198605) Hereditary late-onset Parkinson disease (ORDO: Orphanet_411602)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_EZ01 (ND34267)
Sex of cell	Male
Age at sampling	63Y
Category	Induced pluripotent stem cell
Publications	PubMed=34736041; DOI=10.1016/j.scr.2021.102569 Novak G., Finkbeiner S., Skibinski G., Skupin A. Generation of two human induced pluripotent stem cell lines from fibroblasts of unrelated Parkinson's patients carrying the G2019S mutation in the LRRK2 gene (LCSBi005, LCSBi006). Stem Cell Res. 57:102569-102569(2021)
Cell line databases/resources	hPSCreg; LCSBi006-A
Biological sample resources	BioSamples; SAMEA10585991
Encyclopedic resources	Wikidata; Q108820777
Entry history
Entry creation	23-Sep-2021
Last entry update	19-Dec-2024
Version number	6