Cellosaurus cell line LCSBi005-A (CVCL

Cross-references
Cell line name	LCSBi005-A
Synonyms	ND29542-LRRK2/PARK8-G2019S-clone 3; ND29542-LRRK2-clone 3; ND29542-clone 3; ND29542-3
Accession	CVCL_A8MB
Resource Identification Initiative	To cite this cell line use: LCSBi005-A (RRID:CVCL_A8MB)
Comments	From: Luxembourg Centre for Systems Biomedicine; Belvaux; Luxembourg. Population: Caucasian. Derived from site: In situ; Skin; UBERON=UBERON_0002097. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:18618; LRRK2; Simple; p.Gly2019Ser (c.6055G>A); ClinVar=VCV000001940; Zygosity=Heterozygous (PubMed=34736041).
Disease	Parkinson disease 8, autosomal dominant (NCIt: C198605) Hereditary late-onset Parkinson disease (ORDO: Orphanet_411602)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_DD52 (ND29542)
Sex of cell	Male
Age at sampling	57Y
Category	Transformed cell line
Publications	PubMed=34736041; DOI=10.1016/j.scr.2021.102569 Novak G., Finkbeiner S., Skibinski G., Skupin A. Generation of two human induced pluripotent stem cell lines from fibroblasts of unrelated Parkinson's patients carrying the G2019S mutation in the LRRK2 gene (LCSBi005, LCSBi006). Stem Cell Res. 57:102569-102569(2021)
Cell line databases/resources	hPSCreg; LCSBi005-A
Encyclopedic resources	Wikidata; Q108820775
Entry history
Entry creation	23-Sep-2021
Last entry update	19-Dec-2024
Version number	5