ID   ASTC-a-1 SCAT3
AC   CVCL_A8JW
DR   Wikidata; Q108819857
RX   PubMed=15958279;
RX   PubMed=20714087;
CC   Population: Chinese.
CC   Characteristics: Transfected with the SCAT3 reporter for caspase activation. SCAT3 comprises the ECFP (enhanced cyan fluorescent protein) and Venus proteins linked by an 18 amino acid peptide that includes DEVD, a CASP3 cleavage sequence.
CC   Genetic integration: Method=Transfection; Gene=FPbase; 27HOS; ECFP (Note=Cyan fluorescent protein derived from GFP).
CC   Genetic integration: Method=Transfection; Gene=FPbase; YUJWJ; Venus (Note=Bright yellow fluorescent protein derived from GFP).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
DI   NCIt; C3512; Lung adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_C867 ! ASTC-a-1
CA   Cancer cell line
DT   Created: 23-09-21; Last updated: 10-09-24; Version: 5
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RX   PubMed=15958279; DOI=10.1016/j.canlet.2005.04.036;
RA   Wu Y.-X., Xing D., Luo S.-M., Tang Y.-H., Chen Q.;
RT   "Detection of caspase-3 activation in single cells by fluorescence
RT   resonance energy transfer during photodynamic therapy induced
RT   apoptosis.";
RL   Cancer Lett. 235:239-247(2006).
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RX   PubMed=20714087; DOI=10.3233/XST-2010-0261;
RA   Guo W.-J., Chen T.-S., Wang X.-P., Chen R.;
RT   "Taxol induces concentration-dependent apoptotic and paraptosis-like
RT   cell death in human lung adenocarcinoma (ASTC-a-1) cells.";
RL   J. Xray Sci. Technol. 18:293-308(2010).
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