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Cellosaurus HepG2-N10 (CVCL_A8IF)

[Text version]
Cell line name HepG2-N10
Synonyms HepN10
Accession CVCL_A8IF
Resource Identification Initiative To cite this cell line use: HepG2-N10 (RRID:CVCL_A8IF)
Comments From: Xia, Ning-Shao; Xiamen University; Xiamen; China.
Population: Caucasian.
Virology: Transfected with a hepatitis B virus (HBV) subtype adw2 genome.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
Publications

PubMed=18313149; DOI=10.1016/j.antiviral.2007.11.011
Xu J., Wang J., Deng F., Hu Z.-H., Wang H.-L.
Green tea extract and its major component epigallocatechin gallate inhibits hepatitis B virus in vitro.
Antiviral Res. 78:242-249(2008)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A8IF
Anatomy/cell type resources BTO; BTO_0006301
Encyclopedic resources Wikidata; Q107115336
Entry history
Entry creation20-May-2021
Last entry update19-Dec-2024
Version number8