Cellosaurus M9-ENL1 (CVCL_A8IE)
| Cell line name | M9-ENL1 |
|---|---|
| Synonyms | M9 ENL1; M9ENL1 |
| Accession | CVCL_A8IE |
| Resource Identification Initiative | To cite this cell line use: M9-ENL1 (RRID:CVCL_A8IE) |
| Comments | Characteristics: Expresses a transfected KMT2A-MLLT1 (MLL-ENL) fusion protein. Mimics the features of primary human pro-B cell acute lymphoblastic leukemia (PubMed=22160482). Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:7132; KMT2A (Note=KMT2A-MLLT1 fusion). Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:7134; MLLT1 (Note=KMT2A-MLLT1 fusion). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo. Transformant: KMT2A-MLLT1. Omics: Transcriptomics; Microarray. Derived from site: In situ; Umbilical cord blood; UBERON=UBERON_0012168. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Age at sampling | <1D |
| Category | Transformed cell line |
| Publications | PubMed=22160482; DOI=10.1182/blood-2011-01-330019 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q107115912 |
| Gene expression databases | GEO; GSM838434
GEO; GSM838435 GEO; GSM838436 |
| Entry history | |
| Entry creation | 20-May-2021 |
| Last entry update | 10-Apr-2025 |
| Version number | 8 |