ID   HS181 EGFP-2A-RUNX1c
AC   CVCL_A8HS
SY   HS181 pRRL-EF1a-EGFP-2A-RUNX1c-PGK-Neo
DR   Wikidata; Q107115363
RX   PubMed=28869683;
WW   https://www.isciii.es/QueHacemos/Servicios/BIOBANCOS/BNLC/Lists/Lneas%20embrionarias/Attachments/34/Caracteristicas%20-%20Solicitud_Deposito_linea_HS18_RUNX1c.pdf
WW   https://www.isciii.es/QueHacemos/Servicios/BIOBANCOS/BNLC/Lists/Lneas%20embrionarias/Attachments/34/Anexo%20-%20Anexo_HS181_RUNXc-2.pdf
CC   Part of: Spanish Stem Cell Bank (Banco Nacional de Lineas Celulares) collection.
CC   From: Centre for Genomics and Oncological Research (GENYO); Granada; Spain.
CC   Characteristics: Transduced with a pRRL-EF1a-EGFP-2A-RUNX1c-PGK-Neo construct.
CC   Transfected with: HGNC; 10471; RUNX1 (isoform AML-1C).
CC   Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
CC   Cell type: Embryonic stem cell; CL=CL_0002322.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_C229 ! HS181
SX   Female
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 20-05-21; Last updated: 29-06-23; Version: 4
//
RX   PubMed=28869683; DOI=10.1002/stem.2700;
RA   Navarro-Montero O., Ayllon V., Lamolda M., Lopez-Onieva L., Montes R.,
RA   Bueno C., Ng E.S., Guerrero-Carreno X., Romero T., Romero-Moya D.,
RA   Stanley E.G., Elefanty A.G., Ramos-Mejia V., Menendez P., Real P.J.;
RT   "RUNX1c regulates hematopoietic differentiation of human pluripotent
RT   stem cells possibly in cooperation with proinflammatory signaling.";
RL   Stem Cells 35:2253-2266(2017).
//