Cellosaurus logo
expasy logo

Cellosaurus MAIL8-19 (CVCL_A8GJ)

[Text version]
Cell line name MAIL8-19
Accession CVCL_A8GJ
Resource Identification Initiative To cite this cell line use: MAIL8-19 (RRID:CVCL_A8GJ)
Comments Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:16412; NLRC4 (Note=With p.Leu152_Ala1024del, CARD domain, C12N2 construct).
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:5331; NOD2 (Note=With p.Met1_Ala216del, NACHT+LRR domains, C12N2 construct).
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:16608; PYCARD.
Genetic integration: Method=Transfection/transduction; Gene=FPbase; 1XF1B; GFP (Note=avGFP; original A.victoria green fluorescent protein).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=15701651; DOI=10.1074/jbc.M412284200
Hasegawa M., Imamura R., Kinoshita T., Matsumoto N., Masumoto J., Inohara N., Suda T.
ASC-mediated NF-kappaB activation leading to interleukin-8 production requires caspase-8 and is inhibited by CLARP.
J. Biol. Chem. 280:15122-15130(2005)

PubMed=16964285; DOI=10.1038/sj.onc.1209965
Hasegawa M., Kawase K., Inohara N., Imamura R., Yeh W.-C., Kinoshita T., Suda T.
Mechanism of ASC-mediated apoptosis: bid-dependent apoptosis in type II cells.
Oncogene 26:1748-1756(2007)

Cross-references
Encyclopedic resources Wikidata; Q107115928
Entry history
Entry creation20-May-2021
Last entry update19-Dec-2024
Version number6