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Cellosaurus HT52 (CVCL_A8FH)

[Text version]
Cell line name HT52
Accession CVCL_A8FH
Resource Identification Initiative To cite this cell line use: HT52 (RRID:CVCL_A8FH)
Comments Monoclonal antibody isotype: IgG1, kappa.
Monoclonal antibody target: UniProtKB; O00206; Human TLR4.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_2199 (Sp2/0-Ag14)
Category Hybridoma
Publications

PubMed=22499954; DOI=10.1093/intimm/dxs053
Tsukamoto H., Fukudome K., Takao S., Tsuneyoshi N., Ihara H., Ikeda Y., Kimoto M.
Multiple potential regulatory sites of TLR4 activation induced by LPS as revealed by novel inhibitory human TLR4 mAbs.
Int. Immunol. 24:495-506(2012)

PubMed=26602081; DOI=10.1016/j.febslet.2015.11.018
Tsukamoto H., Ukai I., Yamagata Y., Takeuchi S., Kubota K., Kozakai S., Suzuki N., Kimoto M., Tomioka Y.
Leucine-rich repeat 2 of human Toll-like receptor 4 contains the binding site for inhibitory monoclonal antibodies.
FEBS Lett. 589:3893-3898(2015)

PubMed=28741733; DOI=10.1002/1873-3468.12768
Tsukamoto H., Yamagata Y., Ukai I., Takeuchi S., Okubo M., Kobayashi Y., Kozakai S., Kubota K., Numasaki M., Kanemitsu Y., Matsumoto Y., Tomioka Y.
An inhibitory epitope of human Toll-like receptor 4 resides on leucine-rich repeat 13 and is recognized by a monoclonal antibody.
FEBS Lett. 591:2406-2416(2017)

Cross-references
Encyclopedic resources Wikidata; Q107115379
Entry history
Entry creation20-May-2021
Last entry update21-Mar-2023
Version number3