Cellosaurus HEK-Blue RANKL (CVCL_A8CJ)
| Cell line name | HEK-Blue RANKL |
|---|---|
| Accession | CVCL_A8CJ |
| Resource Identification Initiative | To cite this cell line use: HEK-Blue RANKL (RRID:CVCL_A8CJ) |
| Comments | Characteristics: Designed to detect bioactive human and mouse TNFSF11/RANKL by monitoring the activation of the NF-kappaB and AP-1 pathway. Characteristics: SEAP (secreted ALPP) reporter cell line, in this cell line SEAP is under the control of a promoter with NF-kappaB and AP-1-binding sites. Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:439; ALPP. Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:11908; TNFRSF11A. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P33967; B.cereus Bsr. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR). Transformant: NCBI_TaxID; 28285; Adenovirus 5. Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_0045 (HEK293) |
| Sex of cell | Female |
| Age at sampling | Fetus |
| Category | Transformed cell line |
| Web pages | https://www.invivogen.com/hek-blue-rankl |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q107115280 |
| Entry history | |
| Entry creation | 20-May-2021 |
| Last entry update | 19-Dec-2024 |
| Version number | 7 |