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Cellosaurus HEK-Blue IL-10 (CVCL_A8CF)

[Text version]
Cell line name HEK-Blue IL-10
Accession CVCL_A8CF
Resource Identification Initiative To cite this cell line use: HEK-Blue IL-10 (RRID:CVCL_A8CF)
Comments Characteristics: Designed to detect bioactive human IL10 (and to a lesser extent mouse IL10) by monitoring the activation of the STAT3 pathway (InvivoGen).
Characteristics: SEAP (secreted ALPP) reporter cell line, in this cell line SEAP is under the control of the STAT3 promoter.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:439; ALPP.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:5964; IL10RA.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:5965; IL10RB.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:11364; STAT3.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P33967; B.cereus Bsr.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Web pages https://www.invivogen.com/hek-blue-il10
Cross-references
Encyclopedic resources Wikidata; Q107115260
Entry history
Entry creation20-May-2021
Last entry update19-Dec-2024
Version number8