Cellosaurus 293-SARS2-S-dfur (CVCL_A7YJ)
| Cell line name | 293-SARS2-S-dfur |
|---|---|
| Accession | CVCL_A7YJ |
| Resource Identification Initiative | To cite this cell line use: 293-SARS2-S-dfur (RRID:CVCL_A7YJ) |
| Comments | Group: SARS-CoV-2 research cell line. Characteristics: Stable expression of the SARS-CoV-2 Spike protein with an inactive furin (dfur) cleavage site facilitating improved surface expression and detection for flow cytometry. For optimal expression, the C-terminal ER-retention signal has been removed (InvivoGen). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P0DTC2; Human SARS coronavirus 2 (SARS-CoV-2) spike protein (S). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P33967; B.cereus Bsr. Transformant: NCBI_TaxID; 28285; Adenovirus 5. Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_0045 (HEK293) |
| Sex of cell | Female |
| Age at sampling | Fetus |
| Category | Transformed cell line |
| Web pages | https://www.invivogen.com/293-sars2-spike |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q107113199 |
| Entry history | |
| Entry creation | 20-May-2021 |
| Last entry update | 10-Sep-2024 |
| Version number | 6 |