Cellosaurus 293-SARS2-S (CVCL_A7YI)
| Cell line name | 293-SARS2-S |
|---|---|
| Accession | CVCL_A7YI |
| Resource Identification Initiative | To cite this cell line use: 293-SARS2-S (RRID:CVCL_A7YI) |
| Comments | Group: SARS-CoV-2 research cell line. Characteristics: Stable expression of the SARS-CoV-2 Spike protein. For optimal expression, the C-terminal ER-retention signal has been removed. Has a functional furin cleavage site. Recommended for cell-cell fusion assays with ACE2-expressing cells (InvivoGen). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P0DTC2; Human SARS coronavirus 2 (SARS-CoV-2) spike protein (S). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P33967; B.cereus Bsr. Transformant: NCBI_TaxID; 28285; Adenovirus 5. Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_0045 (HEK293) |
| Sex of cell | Female |
| Age at sampling | Fetus |
| Category | Transformed cell line |
| Web pages | https://www.invivogen.com/293-sars2-spike |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q107113197 |
| Entry history | |
| Entry creation | 20-May-2021 |
| Last entry update | 10-Sep-2024 |
| Version number | 6 |