Cellosaurus HEK-293T-hACE2 (CVCL_A7UK)
| Cell line name | HEK-293T-hACE2 |
|---|---|
| Synonyms | 293T-ACE2 |
| Accession | CVCL_A7UK |
| Resource Identification Initiative | To cite this cell line use: HEK-293T-hACE2 (RRID:CVCL_A7UK) |
| Comments | Group: SARS-CoV-2 research cell line. Characteristics: Expresses ACE2 under the control of the EF1a promoter (BEI_Resources=NR-52511). Genetic integration: Method=Transfection/transduction; Gene=HGNC; 13557; ACE2. Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen. Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo. Transformant: NCBI_TaxID; 28285; Adenovirus 5. Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA). Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_0063 (HEK293T) |
| Sex of cell | Female |
| Age at sampling | Fetus |
| Category | Transformed cell line |
| Publications | PubMed=33495308; DOI=10.1126/science.abf9302; PMCID=PMC7963219 |
| Cross-references | |
| Cell line collections (Providers) | BEI_Resources; NR-52511 |
| Encyclopedic resources | Wikidata; Q107115255 |
| Entry history | |
| Entry creation | 20-May-2021 |
| Last entry update | 10-Sep-2024 |
| Version number | 6 |