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Cellosaurus HEK-293T-hACE2 (CVCL_A7UK)

[Text version]
Cell line name HEK-293T-hACE2
Synonyms 293T-ACE2
Accession CVCL_A7UK
Resource Identification Initiative To cite this cell line use: HEK-293T-hACE2 (RRID:CVCL_A7UK)
Comments Group: SARS-CoV-2 research cell line.
Characteristics: Expresses ACE2 under the control of the EF1a promoter (BEI_Resources=NR-52511).
Transfected with: HGNC; 13557; ACE2.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) [Note=tsA].
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0063 (HEK293T)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line

PubMed=33495308; DOI=10.1126/science.abf9302
Starr T.N., Greaney A.J., Addetia A., Hannon W.W., Choudhary M.C., Dingens A.S., Li J.Z., Bloom J.D.
Prospective mapping of viral mutations that escape antibodies used to treat COVID-19.
Science 371:850-854(2021)

Cell line collections (Providers) BEI_Resources; NR-52511
Encyclopedic resources Wikidata; Q107115255
Entry history
Entry creation20-May-2021
Last entry update05-Oct-2023
Version number5