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Cellosaurus Sf-21-CB (CVCL_A7NB)

[Text version]
Cell line name Sf-21-CB
Synonyms SF-21 CB; Sf21-CB
Accession CVCL_A7NB
Resource Identification Initiative To cite this cell line use: Sf-21-CB (RRID:CVCL_A7NB)
Comments Group: Insect cell line.
Group: Recombinant protein production insect cell line.
Group: Vaccine production cell line.
Biotechnology: Used for the production of the MSD Animal Health porcine circovirus type 2 (PCV2) vaccine Porcilis PCV. Used to produce the PCV2 ORF2 capsid protein.
Biotechnology: Used for the production of the MSD Animal Health classical swine fever virus (CSFV) vaccine Porcilis Pesti. Used to produce the CSFV envelope glycoprotein E2.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Species of origin Spodoptera frugiperda (Fall armyworm) (NCBI Taxonomy: 7108)
Hierarchy Parent: CVCL_0518 (Sf21)
Sex of cell Female
Age at sampling Pupal stage
Category Spontaneously immortalized cell line
Web pages https://www.ema.europa.eu/en/documents/scientific-discussion/porcilis-pesti-epar-scientific-discussion_en.pdf
https://www.ema.europa.eu/en/documents/assessment-report/porcilis-pcv-id-epar-public-assessment-report_en.pdf
Publications

PubMed=22265860; DOI=10.1016/j.vaccine.2012.01.016
Cox M.M.J.
Recombinant protein vaccines produced in insect cells.
Vaccine 30:1759-1766(2012)

Cross-references
Encyclopedic resources Wikidata; Q107116917
Entry history
Entry creation20-May-2021
Last entry update29-Jun-2023
Version number4